Industry Sponsors SMN2018

Award Sponsors

Metabolomics Society

Molecular Omics

Gold Sponsors

Anatune

LECO UK

Metabolon

Royal Society of Chemistry: Analytical Division

Sciex

Shimadzu

Thermo Fisher Scientific

Waters

Silver Sponsors

Crawford Scientific

IonBench

Bronze Sponsors

Agilent

Biocrates

KRSS Ltd

SpectralWorks

 


Award Sponsors


Metabolomics Society

The Metabolomics Society, of which the Scottish Metabolomics Network is an affiliate, is dedicated to promoting the growth, use and understanding of metabolomics in the life sciences. The Metabolomics Society is an independent, non-profit organization, governed by a board of directors composed of dedicated members of the metabolomics community but ultimately responsive to its members. The Metabolomics Society's vision is to become the premier organization devoted to the development of metabolism-based research. Constituted in 2004, the Metabolomics Society now has more than 1,000 members in more than 40 countries.

Our Mission:

1.    To promote the growth and development of the field of metabolomics internationally,

2.    To provide the opportunity for collaboration and association among the workers in that science and in related sciences and connections between academia, government and industry in the field of metabolomics

3.    To provide opportunities for presentation of research achievements and creation of workshops, and

4.    To promote the publication of meritorious research in the field.

metabolomicssociety.org


Molecular Omics

 

Published by the Royal Society of Chemistry (a not-for-profit Publisher), Molecular Omics is a new journal for the –omics sciences led by Editorial Board Chair Professor Robert Moritz.

Molecular Omics is striving to publish research of high quality and significance focusing on molecular level experimental and bioinformatics research in the –omics sciences, including genomics, proteomics, transcriptomics and metabolomics.

We especially welcome multidisciplinary papers that present studies combining different types of –omics, or the interface of –omics and other fields, such as systems biology or chemical biology.

For those that publish with us we offer:

·       Indexing in MEDLINE

·       No submission/publication charges, no page limits, and free colour

·       Rapid publication times

·       Open access publishing options

·       Free electronic reprints of their own paper

·       The ability to submit after pre-print (e.g. in bioRxiv and ChemRxiv)

All primary research is published as Research Articles, which encompass both full paper and communication styles with no strict page limits.

You can find out more about the journal at http://rsc.li/molomics and hear about the latest metabolomics related research published by joining our e-alerts.


Royal Society of Chemistry: Analytical Division

www.rsc.org

 

Gold Sponsors


Anatune

Anatune are the specialists in chromatography & mass spectrometry innovation, sample handling and automation.

As an enabling technologies partner for Chromatography, Mass Spectrometry and Automation we deliver quality results you can trust, on-time, on budget and on-value.

We are an Agilent value-added-reseller (VAR) and the UK distributors for GERSTEL and Syft Technologies.

We integrate fully automated sample handling with chromatography and mass spectrometry systems, either as upgrades or as complete analyzers.

Our innovative, flexible and modular solutions deliver improved data quality, increased sample capacity, faster turn-around times and lower total costs.

We have been supplying solutions to the UK metabolomics community for the last 15 years and all out customers benefit from comprehensive applications and field service support.

Our solutions for metabolomics include integrated platform technologies for untargeted (discovery) metabolomics and targeted metabolic phenotyping (biomarker verification/validation) that combine fully automated sample preparation, instrumental analysis and automated data processing, analysis and reporting.


LECO UK

As the established leader in GC-MS metabolomics LECO is your partner in providing products that have the accuracy, resolving power, and speed to characterise the most complex metabolite profiles, with methods validated at the highest level by the industry’s most demanding researchers.

LECO’s Pegasus legacy instruments were well established in the metabolomic community with the derivatisation friendly source seen by many as a must-have. LECO have improved on the legacy range and recently brought out the PegasusBT, a bench top instrument with the sensitivity of a single quad but far faster, analysing over 50 million amu per second, sub nominal mass accuracy and with the new StayClean® source.

The GC-HRT+  is LECO’s industry leading accurate mass instrument with up to 50,000 resolution, 200 spectra per second and sub ppm mass accuracy.

As is to be expected from LECO, all instrument can upgrade with a GCxGC option - either the highly accurate liquid nitrogen cooled quad jet modulator, or a consumable free cooling quad jet.

When combined with LECO’s True Signal Deconvolution® and metabolite-specific libraries, such as the LECO/Fiehn metabolomics library LECO’s instruments provide scientists with superior insight into biological content, thus generating superior understanding of experimental variation.

Metabolomics presents challenges for both the analytical methods used and the data reduction required to interpret the results. No single analytical technique can be used for complete characterization of the metabolome, and no metabolome has been completely characterized yet. Whilst LC investigates the secondary and tertiary metabolites, GC-MS provides an established method to analyse the primary metabolome.

For further information and application notes, visit the LECO UK Metabolomic page.

Allow yourself to see the complete picture with metabolomics solutions from LECO.

uk.leco-europe.com


Metabolon

Metabolon, Inc. is the world’s leading health technology company focused on advancing metabolomics. Our AI-driven Precision Metabolomics™ platform detects thousands of biologically important molecules and gives unprecedented insights into health and underlying biological function. These data are driving advances in precision medicine, biomarker discovery, diagnostic testing, and population health initiatives.

Our expertise is also accelerating research and product development across the pharmaceutical, biotechnology, consumer products, agriculture and nutrition industries, as well as academic and government organizations.

Your Partner for Biomarker Discoveries & Metabolomics Solutions

Precision Metabolomics is a revolutionary technology for obtaining the most comprehensive, high-quality and accurate metabolomics data available. Our technology and workflow produce a full picture of the metabolome and map metabolites to their key biochemical pathways.

We offer a full range of metabolomics solutions - from discovery to targeted assays - that empower you at every stage of research.

Whether you want to survey the entire metabolome, only complex lipids, or just a few key pathways or metabolites, our team of experts will work with you to clearly define your goals and develop a customized plan to meet them.

 

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Metabolon was founded in 2000 and has locations in Research Triangle Park, North Carolina and Potsdam, Germany. For more information, please visit www.metabolon.com or follow us on LinkedIn or Twitter.


Royal Society of Chemistry: Analytical Division

www.rsc.org


Sciex

Metabolomics research not only holds the key to revealing interactions taking place in biological complexes, it is instrumental to discovering new drugs, biomarkers and uncovering disease pathology. SCIEX offers a complementary portfolio of solutions to measure, process, characterise and translate your research into biological knowledge.

Discovery Metabolomics

The SCIEX discovery metabolomics workflow can uncover and identify new compounds that could be putative biomarkers or key elements of important metabolic pathways. With the power of the TripleTOF® system, there's no need to choose between data acquisition methods. With one sample injection, you can process your data to screen for unknown metabolites or focus on only those compounds of interest with a targeted metabolite screening approach.

  • Unknown Metabolite Screening: When little information exists about a sample, or new information is desired, this data processing approach will allow you to discover all compounds that are different between samples. With XCMSplussoftware you can simultaneously quantify and identify thousands of features across hundreds of samples and search the METLIN database to identify metabolites of interest.

  • Targeted Metabolite Screening: When you want to extract information for known compounds, this data processing approach enables hypothesis-driven data analysis. Using MasterView™ software, and the Accurate Mass Metabolite Spectral Library you can concentrate on finding and quantifying changes between known compounds, such as all metabolites within a specific biochemical pathway. Then MultiQuant™ software and MarkerView™ software enables rigorous quantitation and statistical analysis of those compounds across hundreds of samples.

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Targeted Metabolomics

Confirm and identify quickly

With targeted analysis, specific biological hypotheses can be tested by designing an MS experiment to detect and quantify a subset of analytes from biological systems. When paired with SelexION™ Ion Mobility Technology, you'll be able to distinguish compounds of interest from isobaric and near isobaric interferences with ease.

This could be done on a standard triple quadrupole mass spectrometer, but a QTRAP 6500 System offers so much more:

  • Highest sensitivity and accurate quantitation using MRM or MRM3

  • High-sensitivity, full-scan MS/MS to confirm metabolite identity using unique TripleTrap Scanning of the QTRAP System and the integrated Linear Accelerator Trap



 

Thermo Fisher Scientific

Comprehensive metabolomics analysis

Biology is complex. To decipher these complexities, metabolomics analysis demands sophisticated analytical technologies and software solutions. We aim to address the whole workflow from sample preparation, sample separation by a range of chromatographic systems and columns, sample analysis by state-of-the-art mass spectrometry and other related techniques and subsequent data processing and analysis.

Our proven scientific network, publications and pioneering solutions driven by Thermo Scientific™ Orbitrap™ mass spectrometers enable broader and deeper analyses into the metabolome. Our industry-leading breadth in chromatographic separations, GC, LC and IC, combined with the technical depth of our systems and consumables, together produce novel, stringent and reproducible results for high impact discoveries whether that be in targeted or untargeted metabolomics, lipidomics or beyond.

Deeper and broader analysis for untargeted metabolomics

Untargeted metabolomics compares the relative abundances of all metabolites in multiple samples, often complex, without prior knowledge. Both the separation techniques and the high resolution accurate mass (HRAM) Orbitrap MS must be highly reproducible, have high sensitivity and be capable of measuring a wide dynamic range of compounds ranging from very hydrophilic to hydrophobic metabolites for comprehensive coverage.

Thermo Scientific metabolomics software is specially designed to mine the rich HRAM Orbitrap data to convert large data sets into meaningful insights.

Targeted profiling and quantitation solutions

Identified biomarkers from either untargeted metabolomics experiments, or hypothesis-driven from the literature, can be verified or validated where usually a limited number of compounds are quantified in a large set of samples.

For highest selectivity and confirmation, HRAM Orbitrap mass spectrometry is the technology of choice for verification of putative biomarkers. Moving through to high-throughput quantitation, SRM analysis on the Thermo Scientific™ TSQ™ triple quadrupole mass spectrometers is the solution of choice.

Comprehensive lipidomics solutions

Lipidomics is a field of metabolomics that has evolved into a class all its own and aims to map and quantify lipid species sets within a cell or tissue to identify biomarkers and elucidate metabolism at the cellular level. Lipid species are diverse and complex, and the development of HRAM Orbitrap MS has risen to the challenge of lipid analysis, offering an unprecedented level of sensitivity, selectivity and precision.

www.thermofisher.com/metabolomics

www.thermofisher.com


Waters

If you are performing research in the Metabolomic and Lipidomics area Waters Corporation is uniquely placed to provide exclusive tools to help you gain success in your research. We are keen to understand what drives your research and are open to collaborate to introduce you to new technologies and innovations to help advance your science.

Waters have a catalogue of innovative mass spectrometry products that can help you to achieve your metabolomic goals. Amongst these the Ion Mobility (IMS) and SONAR™ acquisition modes are superb tools to help with the sample complexity inherent to metabolomic analyses.

Ion Mobility (IMS)

  • Provides orthogonal separation power - IMS resolution sufficient to separate ions not amenable to m/z separation. i.e. isomers, conformers, ions of different molecular class or charge-state

  • Provides increased peak capacity - providing significant gains in selectivity (analytical peak capacity) and specificity (confidence in results), when compared to the use of m/z separation alone

SONAR (Stop looking, Start Seeing)

  • By sliding a resolving quadrupole window over a specified mass range during an MS scan, the quadrupole separates co-eluting precursor masses by scanning the mass range, and transmitting them in sequence. Fragment ions from different precursors can then be recorded separately and assigned with confidence

  • Allows you to qualitatively identify metabolites in complex samples and extract high resolution quantitative information from a single injection

  • SONAR provides increased selectivity compared to a conventional DIA experiment while collecting data at UPLC compatible speeds

When it comes to data interpretation we have best in class software packages to help take the headache out of feature identification;

Metabolic Profiling CCS Library

  • When using IMS acquisition you can use the CCS of analysed molecules as an additional uniquely identifying feature

  • The Waters Metabolic Profiling CCS Library includes more than 900 measurements of collision cross section (CCS) values, and more than 600 MS/MS spectra

Progenesis QI

  • Progenesis QI is small molecule discovery analysis software; a revolutionary ‘difference engine’

  • The built-in Metascope search engine enables ID of compounds using mass, RT, fragmentation spectra, CCS

  • Uses publicly available and in-house databases

  • The co-detection workflow results in improved matching, peak picking and normalisation, which allows robust uni-variate and multi-variate statistical analysis and false positive correction

  • Can handle high numbers of highly complex samples

METLIN® MS/MS Library for Progenesis QI

  • Implementation of the METLIN library directly within Progenesis QI

  • One of the most comprehensive and widely used metabolite databases, represents the largest MS/MS collection of metabolite data generated at multiple collision energies in positive and negative ionization modes

  • Includes over 240,000 different compounds, with over 13,900 individually analyzed with measured MS/MS and over 220,000 with in silico MS/MS data

Got a project you'd like to discuss? Meet us at a Metabolomics Conference near you in 2018:
Metabolomics 2018, Seattle, USA (June 24-28)
Nordic Metabolomics Conference, Örebro, Sweden (August 26-28)
CBL Lipid Fluxes and Metabolism Conference, Helsinki, Finland (Sept 4-7)
Scottish Metabolomics Network Symposium, Dundee, Scotland (Nov 1-2)

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Siver Sponsors


Crawford Scientific

Crawford Scientific is the largest UK distributor specialising in Chromatography consumables, training and consultancy. Our independent status and team of expert chromatographers allows us to offer the products and services which we believe are right for your instruments and applications. We supply and support laboritories in all industries including academia, pharmaceutical, envoronmental and food and drink and across many departments specialising in areas such as metabolomics, proteomics and lipidomics.

What we can offer to support your laboratory needs

We work with major manufacturers of chromatography consumables including: Agilent; Thermo Fisher Scientific; YMC; Silicycle; SIELC; Daicel; Porvair Sciences. Please get in touch for information and recommendations on the latest column technologies, applications and highly competitive pricing!

Our technical support specialists have decades of experience in all areas of chromatography including LC, GC and MS -  allowing us to offer support in troubleshooting, instrument and applications issues and recommendations. As a Crawford Scientific customer, you have direct access to this information and knowledge.

Supporting the metabolomics community our team are able to offer a range of products from a large pool of manufacturers. With specialists in LCMS Crawford Scientific can deliver customised training as well as both remote and on site support. Our team have specialist experience in HILIC applications and are happy to advise recommendations, supported by our customised loan toolbox for evaluation or option to “Buy&Try”.

As the UK’s main distributor for Porvair sciences we are able to provide a variety of products to meet your protein crash needs as well as offering custom designed microplate evaporators to suit all sizes of operation.

Get in touch

Do you have a challenging method? Unsure of the most up to date options available and how to select the best products for your application? Looking to find more cost effective solutions? Please get in touch and see how we can support you!

www.crawfordscientific.com

victoria@crawfordscientific.com           vascar@crawfordscientific.com


IonBench

IonBench supplies pharmaceutical, environmental, clinical and university laboratories. Our products are designed to ease the day to day use of your LC/GC/MS, by providing a significant number of features that makes your working conditions better.

Our manufacturing plant ships worldwide on a daily basis. We use a rigorous program including continuous monitoring of each operation and systematic identification of each assembled part during manufacturing. The engineering department will spend time on your projects to ensure the core ideas of your goals and make them real.

We have two main lines of laboratory furniture for the LC/GC/MS field : Ionbench MS & Ionbench LC.

Ionbench MS lab furniture products integrate mass spectrometer peripherals, include a vacuum pump enclosure (up to -80% in noise perception, lined with acoustic foam & heat resistant materials) and successfully protect turbomolecular pumps from the different vibrations.

Ionbench LC lab furniture products contribute to lab safety & productivity. Easily optimise the global performance of your LC/MS combination. Avoid any chromatography peak tailing (adjustable height) and get a nice flexibility on multiple configurations (caster wheels).

On top of that, the LC & MS Benches from Ionbench are always fully movable! For an easy access to the rear of the instruments, our benches are on caster wheels. You no longer need to climb on the work-surfaces to access your instrument. With IonBench, you benefit from significant 30% space saving as you do not need to dedicate space for an access corridor. If you need to access to the rear of the instrument, it is a very easy task to do !

Many accessories are available : Drawers, information control package, CPU holder, solvent waste storage, heat removal module, oil drain pump, etc. Also great compatibility with MS manufacturers such as Agilent, Bruker, Jeol, Leco, Perkin Elmer, Sciex, Shimadzu, Thermo Scientific, Waters...

Got a suggestion? Contact us at www.ionbench.com ! Thank you for your interest in helping us making your lab space healthier, quieter and safer.

www.ionbench.com


 

Bronze Sponsors


Agilent


Metabonomics Health and Biocrates

Biocrates and Metanomics Health have recently merged to create a new global leader in Metabolomics and early disease detection. As a total solution provider, the merged companies provide the broadest technology and product portfolio in the industry. Extensive expertise in targeted and global metabolic profiling, customized assay development, targeted screening kits, data interpretation, and Dx/CDx Kit development make Biocrates and Metanomics Health the preferred partner for all your requirements in metabolite analysis.

Biocrates’ metabolomics kits allow for the analysis of up to 400 metabolites across multiple analyte classes in a single run. These kits have contributed to more than 800 scientific publications and are being used in more than 100 mass spectrometry laboratories throughout the world. The whole range of analytical and data interpretation services is available through the company’s service laboratories in Berlin, Germany and Innsbruck, Austria.

Biocrates’ technology is established in more than hundred mass spectrometry laboratories around the world. It has contributed to more than 900 scientific publications, many of which in leading journals for basic, clinical and epidemiological sciences.

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KRSS

KRSS Ltd is an independent Mass Spec and chromatography sales and service company in the UK/Europe & Asia - offering service, instruments and consumables to the pharmaceutical, environmental, forensic, life sciences, food, biotechnology, clinical and academic markets. Our expertise in the LCMS Service, GCMS Service and MS equipment has allowed us to lead the way in developing customer focussed support packages. KRSS customises each contract to meet the needs of the individual customer. We put together service packages which maximise the benefit to our customers, whilst giving due consideration to costs.

Our technical team has over 25 years' experience in Mass Spec, LCMS, GCMS, HPLC and GC, allowing us to develop an unrivalled technical expertise and market understanding. This level of expertise enables KRSS to offer personalised solutions for consolidated instrument service, providing our customers a convenient, cost effective plan for all manufacturers' instruments.

www.krssltd.com


SpectralWorks

MS Data Processing for Metabolomics

SpectralWorks Limited provides fast, automated software solutions to handle the large data sets from metabolomics data processing for 1) interrogation of data quality and 2) interpretation of experimental data. AnalyzerPro® is a vendor neutral chromatographic deconvolution package with qualitative and quantitative processing capability including multiple data interrogation and interpretation features such as principal component analysis (with options for data transformation), univariate statistical analysis and graphical representations of retention time and signal drift.

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MS Data Processing Workflow 


 

Industry Sponsors SMN2017

Award Sponsors


Royal Society of Chemistry: Analytical Division

www.rsc.org

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Gold Sponsors


Agilent

www.agilent.co.uk

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Sciex

www.sciex.org

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Shimadzu 

www.shimadzu.co.uk

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Thermo Fisher Scientific

www.thermoscientific.com

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Waters

www.waters.com

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Siver Sponsors


Anatune

 

 

www.anatune.co.uk

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Bronze Sponsors


Advion

www.advion.com

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Cambridge Bioscience

www.bioscience.co.uk

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Glasgow Polyomics

www.polyomics.gla.ac.uk

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Merck

www.merck.co.uk

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Peak Scientific

www.peakscientific.com

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Scottish Universities Life Sciences Alliance (SULSA)

www.sulsa.ac.uk

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VWR

uk.vwr.com

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IonBench

www.ionbench.com

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